REGULATION OF TYPE I IFN PRODUCTION IN PLASMACYTOID DENDRITIC CELLS BY SRC-FAMILY KINASES AND CD28 A thesis submitted in partial satisfaction of the requirements

نویسنده

  • Charles R. Hesser
چکیده

................................................................................................................ ix Introduction ............................................................................................................ 1 Chapter 1: The role of src-family kinases in pDC cytokine production .................. 9 Chapter 2: CD28 acts as a negative regulator of pDC IFN-I production .............. 24 Chapter 3: Potential cross-talk between Cd28, Src-family kinase and PI3K signaling ...................................................................................................... 42 Conclusion ........................................................................................................... 51 Materials and Methods ......................................................................................... 57 References ........................................................................................................... 64

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تاریخ انتشار 2012